Research

Breaking Clots With Sound

Red and black abstract image.

Clots that block blood flow away from the brain are one of the most common causes of strokes for younger people. If caught early, anticoagulants can sometimes resolve the issue, but the treatment fails in 20-40% of cases. Now researchers are investigating a new ultrasound technique capable of quickly and effectively removing these clots.

An illustration of the vortex ultrasound technique breaking up a blood clot.
An illustration of the vortex ultrasound technique breaking up a blood clot.

The group attached a 2 x 2 array of ultrasound transducers to the tip of a catheter like those doctors feed through blood vessels in other interventions. The offset between each ultrasound transducer creates a vortex-like flow when the array is activated. The helical wavefront creates shear stress along the clot’s face, helping to break it up faster. In one test, the new technique broke up a clot and completely restored flow in just 8 minutes. Pharmaceutical treatments take at least 15 hours and average closer to 29 hours.

The team is moving forward to animal trials next and hope, with success there, to bring the technique to clinical studies. (Image credit: abstract – C. Josh, illustration – X. Jiang and C. Shi; research credit: B. Zhang et al.; via Physics World)

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