FYFD

Tag: COVID-19

  • Simulating a Sneeze

    Simulating a Sneeze

    Sneezing and coughing can spread pathogens both through large droplets and through tiny, airborne aerosols. Understanding how the nasal cavity shapes the aerosol cloud a sneeze produces is critical to understanding and predicting how viruses could spread. Toward that end, researchers built a “sneeze simulator” based on the upper respiratory system’s geometry. With their simulator, the team mimicked violent exhalations both with the nostrils open and closed — to see how that changed the shape of the aerosol cloud produced.

    The researchers found that closed nostrils produced a cloud that moved away along a 18 degree downward tilt, whereas an open-nostril cloud followed a 30-degree downward slope. That means having the nostrils open reduces the horizontal spread of a cloud while increasing its vertical spread. Depending on the background flow that will affect which parts of a cloud get spread to people nearby. (Image and research credit: N. Catalán et al.; via Physics World)

    Fediverse Reactions
  • Linking Size and Origin in Droplets

    Linking Size and Origin in Droplets

    Respiratory diseases like measles, flu, tuberculosis, and COVID-19 are all transmitted by droplets. Some are tiny and airborne, capable of traveling long distances. Other drops are larger and only capable of traveling short distances. A new review paper consolidates what we know about these droplets and categorizes them by size and origin.

    It turns out that a droplet’s size can tell us where it originated in the body. The largest type of droplets come from our mouths, lips, and tongues. Some form from filaments of saliva that stretch across our mouths and burst during exhalation. Others originate in our nasal passages where a sneeze can destabilize the mucus film there. These types of droplets are best suited to transmitting diseases that reside in the upper respiratory tract. Coughing, sneezing, singing, and speaking all produce these droplets, but breathing does not.

    In contrast, the smallest classes of droplets come from the bronchial passages of the lungs, where films form after exhalation closes a passage. When we inhale again, the passage reopens, the film breaks up, and tiny droplets flow further into the lungs before getting exhaled. Breathing alone is enough to create and spread these tiny droplets, which are well-suited to spreading diseases that reside deep in the lungs, like tuberculosis.

    In between these extremes are medium-sized droplets created from movement around our vocal cords. The formation mechanism for these droplets is least understood, but they are connected to breathing, coughing, speaking, singing, and so on.

    Ultimately, understanding the mechanics of disease transmission is about knowing how to best prevent transmission. Knowing the size of droplets responsible for transmission lets us prioritize responses that work. For example, if large droplets are the primary transmission mechanism, loose-fitting masks and face masks will stop the spread. But for smaller droplets, ventilation measures and well-fitted N-95 respirators are the better choice. (Image credit: Anton; research credit: M. Pöhlker et al.; via APS Physics)

  • Gathering Safely

    Gathering Safely

    One effect of the COVID-19 pandemic is a renewed interest in the physics of disease transmission and what measures can protect us from airborne respiratory illnesses. This recent study looks at how meetings — whether in classrooms, conferences, or care facilities — can transmit infections. Their mathematical model is able to handle many variables — room size, number of people, length of meeting, breaks between sessions, masking, ventilation, and so on. Without prescribing any one policy, the authors aim to inform decision makers so that they can choose what methods (testing, masking, ventilation, etc.) work best for their event.

    That said, they find that ventilation and periodic breaks between meetings are highly effective in reducing a room’s viral load. Leaving enough time between sessions for ventilation to clear the room was as effective (or more effective) than masking and moderate isolation of those infected. Tools like these are vital in enabling gatherings that keep participants safe. (Image credit: Product School; research credit: A. Dixit et al.; submitted by Kam-Yung Soh)

  • Airflow in the Opera

    Airflow in the Opera

    Like so many other performers, the singers and musicians of New York’s Metropolitan Opera House were left without a way to safely perform when the SARS-CoV-2 pandemic began in early 2020. In search of safe ways to perform and rehearse, the Met turned to researchers at nearby Princeton University, who worked directly with the performers to explore aerosol production and airflow in the context of professional opera.

    Through visualization and other experiments, the team found that the highly-controlled breathing of opera singers actually posed a lower risk for spreading pathogens than typical speaking and breathing. Most of a singer’s voiced sounds are sustained vowels, which produce a slow, buoyant jet that remains close to a singer. The exception are consonants, which created rapid, forward-projected jets.

    In the orchestra, the researchers found that placing a mask over the bell of wind instruments like the trombone reduced the speed and spread of air. One of the highest risk instruments they found was the oboe. Playing the oboe requires a long, slow release of air, but between musical phrases, oboists rapidly exhale any remaining air from their lungs and take a fresh breath. That rapid exhale creates a fast, forceful jet of air that necessitates placing the oboist further from others. (Image credit: top – P. Chiabrando, others – P. Bourrianne et al.; research credit: P. Bourrianne et al.; via APS Physics; submitted by Kam-Yung Soh)

  • Aerosols and Instruments

    Aerosols and Instruments

    Although COVID has disrupted all of our lives, orchestras saw particular disruption, as little was known about how instruments spread aerosol droplets. In this recent study, a team looked at many wind instruments, as played by professional musicians, for the aerosol load and air flow each instrument creates. They found that, on the whole, wind instruments — like flutes, clarinets, trumpets, and others — create aerosol loads comparable to normal speech. The air flow from each instrument comes primarily from the bell (for brass instruments) or tone holes (for woodwinds) and has a much lower velocity than coughing or sneezing. As a result, the flow decays away to the background air-flow after about 2 meters. (Image credit: trumpet – E. Awuy, trombone – Q. Brosseau et al.; research credit: Q. Brosseau et al.)

    Flow from the bell of a trombone disrupts artificial fog.
    As a musician plays a scale on their trombone, flow from the bell is revealed through artificial fog and laser illumination.
  • Inside a Coronavirus Aerosol

    Inside a Coronavirus Aerosol

    This is a glimpse inside a tiny aerosol droplet with a single SARS-CoV-2 coronavirus inside it. The numerical simulation required a team of 50 scientists, 1.3 billion atoms, and the second most powerful supercomputer in the world. By simulating every atom, the researchers hope to observe what happens to a coronavirus in these micron-sized, long-lasting droplets. Does the virus survive? How do variants fare?

    Their simulation shows that the positive charge of the coronavirus’s spike proteins helps attract mucins that shield the virus and protect it from the droplet interface where evaporation could destroy it. Variants like Delta and Omicron have even more positive charge to their spike proteins, giving themselves a better cloak of mucins and potentially making them all the more infectious. Definitely check out the full New York Times write-up for more spectacular visualizations from the work. (Image and research credit: R. Amaro et al.; via NYTimes; submitted by Kam-Yung Soh)

  • Wet Masks Block Droplets Better

    Wet Masks Block Droplets Better

    As wearing face masks for long periods has become more typical, you may have wondered whether a soggy mask offers less protection. All masks — cloth, surgical, and N-95s — get moist from their wearer’s breath. A recent study indicates this isn’t a cause for alarm, though.

    Researchers looked at how relatively high-speed droplets (like those from a cough or sneeze) impact dry and wet masks. These high-speed droplets can break into smaller droplets upon impact with a mask layer. The more layers a mask has, the fewer droplets make it through. But even for single-layer masks*, a moistened mask layer lets fewer droplets through. So you don’t have to worry if it’s a little humid in there. Your mask is still working! (Image credit: top – V. Davidova, other – S. Bagchi et al.; research credit: S. Bagchi et al.; via APS Physics)

    * To be clear, you should be wearing masks that are more than a single layer thick. Personally, I’m still only going into indoor public spaces in an N-95 at this point.

    Droplet penetration through a mask. Top row: dry, single layer mask. Middle row: wet, single layer mask. Bottom row: wet, triple layer mask.
    Droplet penetration through a mask. Top row: dry, single layer mask. Middle row: wet, single layer mask. Bottom row: wet, triple layer mask. When wet, masks permit fewer droplets through.

  • Turbulent Puffs

    Turbulent Puffs

    When a burst of air gets expelled into still surroundings — like when a person coughs — it forms a turbulent puff like the one seen here. Puffs can be surprisingly long-lasting, though these miniature clouds slow down and expand over time. How they behave is critical to understanding the spread of pollution as well as how respiratory illnesses like COVID-19 travel. In this study, researchers found that buoyancy is also a critical factor. When the puff is warmer than its surroundings, it rises higher, lasts longer, and travels further. That might help explain why respiratory illnesses like the flu spread more readily in the winter than in warmer months. (Image and research credit: A. Mazzino and M. Rosti; via Physics World; submitted by Kam-Yung Soh)

  • Controlling Aerosols Onstage

    Controlling Aerosols Onstage

    Few industries saw more disruption from the pandemic than the performing arts. To help orchestras return to the concert hall in a way that keeps performers and audience members safe, researchers have simulated air flow and aerosols around musicians onstage. Some instruments — like the trumpet — are super-spreaders when it comes to aerosol production, and, in the conventional organization of orchestras, those aerosols have to travel through other sections of the orchestra before reaching air vents, putting more musicians at risk.

    (Upper left) Aerosol concentration for an orchestra performing in their original arrangement, with doors to the hall closed; (Upper right) Aerosol concentration in the modified musician arrangement, with doors open; (Bottom row) Time-averaged aerosol concentration in the breathing zone of performers for (left) the original arrangement and (right) with modified seating.
    (Upper row) Aerosol concentration for the orchestra’s original seating arrangement (left) and in the modified arrangement (right). (Bottom row) Time-averaged concentration of aerosol particles in the breathing zone of each musician in the original (left) and modified arrangements (right).

    Using Large Eddy Simulation, researchers looked at alternate seating arrangements for the Utah Symphony that could mitigate these risks. By rearranging the musicians so that instruments that produce lots of aerosols are closer to the air vents and open doors, the team reduced the average concentration of aerosols around musicians by a factor of 100, giving the performers a chance to return to the stage far more safely. (Image credit: top – M. Nägeli, simulation – H. Hedworth et al.; research credit: H. Hedworth et al.; via NYTimes; submitted by Kam-Yung Soh)

  • Airborne Aerosol Transmission of COVID-19

    Airborne Aerosol Transmission of COVID-19

    Early in the COVID-19 pandemic health officials resisted the idea that the novel coronavirus was transmissible through tiny aerosol droplets rather than larger, non-buoyant droplets. One case that made headlines and helped shift opinion was that of an outbreak among patrons of a Guangzhou restaurant traced to a single, pre-symptomatic patient zero. The pattern of who became sick at the carrier’s table and those nearby made little sense unless the restaurant’s air flow played a role in spreading the virus.

    https://www.youtube.com/watch?v=WaZiCqQmO4g

    This paper studies the incident in detail, using an in-house computational fluid dynamics (CFD) code to simulate both airflow in the restaurant and the paths aerosol droplets would follow in that environment. It takes into account flow from the air conditioner and the warm air rising from customers. The study’s predictions of which areas would have the highest concentrations of virus-laden aerosols matches well with the actual pattern of the outbreak. The authors hope that tools like theirs can help prevent future outbreaks by indicating the most dangerous paths for transmission and measures that can block those. (Image credit: Center for Disease Control; video, research, and submission credit: H. Liu et al.)