This glimpse inside a 5-day-old zebrafish’s heart shows why they’re often used as a model organism in cardiac studies. The fish’s heart rate is similar to humans and its two-chamber heart — one atrium and one ventricle, both seen here — serves as a simplified version of ours. Check out the slowed-down section of the video to clearly see blood filling and expanding one chamber before it’s pumped onward. Perhaps the most unusual feature of the zebrafish’s heart is its ability to regenerate; after amputation of up to 20% of its ventricle, the fish can fully regenerate its heart. That’s a pretty incredible recovery, especially when you consider that the heart has to keep pumping the entire time! (Video credit: M. Weber/2023 Nikon Small World in Motion Competition)
Tag: cardiac blood flow
Flow in the Heart
Few flows are more integral to our well-being than blood flow through the heart. Over the course of our lives, our hearts develop from a few cells pushing viscous blood through tiny arteries to the muscular center of a vast circulatory network, capable of powering us through incredible physical feats. What’s most astonishing about all this is that the heart goes through all these changes and adaptations without ever pausing.
Peering into the heart to see it in action is difficult, but researchers today are combining imaging techniques like CT and MRI with computational fluid dynamics to build patient-specific heart models. Not only does this help us understand hearts in general; it’s paving the way toward predicting how a specific treatment may affect a patient. Imagine, for example, being able to simulate and compare different models of an artificial heart valve to see which will work best for a particular patient. We’re not to the point of doing so yet, but it’s a very real possibility in the future.
To see some examples of predicted and measured heart flows, check out this video by J. Lantz. In the meantime, happy Valentine’s Day! (Image credits: Linköping University Cardiovascular Magnetic Resonance Group, video source; via Another Fine Mesh)
Flow Inside the Heart
Inside each of us is a remarkable and constant flow, driven by a muscle that’s always at work. As blood circulates through our bodies, it goes through a surprisingly varied journey. In the heart, as seen above, blood flow is very unsteady and quite turbulent, due to the beating pulse of the heart. As valves open and close and the muscle walls constrict and relax, the rushing blood moves in eddy-filled spurts. In the outer reaches of our capillaries, however, the nature of the flow is quite different. Thanks to smaller vessel sizes and other factors, capillary blood flow is much steadier and more laminar. Viscosity becomes more important, as do the non-Newtonian properties of components in our blood. (Image credit: mushin111/YouTube, source; via Science; submitted by Gary N.)
